IATA Class 6 Division 6.1 Classification

To determine the inhalation toxicity and packing group of a liquid mixture, you must follow the guidelines in Subsection 3.6.1.6. If LC50 data is available, use the provided formulas to determine the estimated LC50 value of the mixture, the estimated volatility of each component, and the ration of volatility to the LC50. If LC50 data is not available, use the packing group criteria listed in Subsection 3.6.1.6.2.

To determine the oral and dermal toxicity of mixtures and classify it into the appropriate packing group, you must first determine the acute LD50 of the mixture. If there is only one active substance, you can calculate the LD50 of the mixture by taking the LD50 value of the active substance and multiplying it by 100. Then, divide that answer by the percentage of the active substance by mass. If a mixture contains more than one active substance, there are three possible approaches for determining the oral and dermal toxicity:

• Obtain acute oral and dermal toxicity data on the mixture.
• Classify the mixture according to the most hazardous substance of the mixture.
• Use the formula provided in Subsection 3.6.1.7.2.2 to calculate an estimate.

The LD50 toxicity data for common pesticides may be obtained from the WHO Recommended Classification of Pesticides by Hazard and Guidelines to Classification. Only use that document to obtain the LD50 value; do not use its classification system as a substitute for the IATA DGR air transport classification.

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